N-PENTYL TRIPHENYLPHOSPHONIUM BROMIDE - Names and Identifiers
N-PENTYL TRIPHENYLPHOSPHONIUM BROMIDE - Physico-chemical Properties
Molecular Formula | C23H26BrP
|
Molar Mass | 413.33 |
Melting Point | 165-168 °C |
Water Solubility | Partly miscible in water. Soluble in methanol and chloroform. |
Solubility | Soluble in water (partly miscible), methanol (almost transparency), lower alcohol, and ch |
Appearance | Light brown to yellow-brown crystalline powder |
Color | White to Almost white |
BRN | 3580453 |
Storage Condition | Inert atmosphere,Room Temperature |
Sensitive | Hygroscopic |
MDL | MFCD00031630 |
N-PENTYL TRIPHENYLPHOSPHONIUM BROMIDE - Risk and Safety
Hazard Symbols | Xn - Harmful
|
Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin.
R22 - Harmful if swallowed
|
Safety Description | S37/39 - Wear suitable gloves and eye/face protection
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S37 - Wear suitable gloves.
|
HS Code | 29319090 |
N-PENTYL TRIPHENYLPHOSPHONIUM BROMIDE - Introduction
pentyltriphenylphosphonium bromide is an organic compound with the chemical formula C24H27BrP. The following is a description of its nature, use, formulation and safety information:
Nature:
pentyltriphenylphosphonium bromide is a white crystal or crystalline powder, soluble in organic solvents such as ethanol and acetone, insoluble in water. It is an organic phosphorus compound that exhibits strong alkalinity in chemical reactions.
Use:
pentyltriphenylphosphonium bromide is commonly used as a reagent in organic synthesis reactions, and its main uses include:
1. Mendelson catalyst: As a Mendelson catalyst, it can catalyze the polymerization of olefins.
2. Maknovnikov reagent: In organic synthesis, it is also used as Maknovnikov reagent for the synthesis of olefins.
3. Preparation of artemisinin: The compound can be used to prepare artemisinin, is an anti-malaria drug.
Method:
The preparation of pentyltriphenylphosphonium bromide is usually carried out by the following reaction:
triphenylphosphine bromoethane → pentyltriphenylphosphonium bromide
Safety Information:
pentyltriphenylphosphonium bromide is an organic compound. Pay attention to the following safety precautions:
1. The compound is an irritating substance and can cause irritation when in contact with skin and eyes. Wear appropriate protective equipment such as gloves and goggles during operation.
2. Avoid inhaling the dust or vapor of the compound and use it in a well-ventilated laboratory environment.
3. The compound may produce toxic gases at high temperatures or open flames, so avoid contact with oxidants.
4. This compound should be stored properly, away from ignition and flammable materials, and keep the container sealed.
Last Update:2024-04-09 02:00:44